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| 生化科研試劑 >> 抗體產品 >> 一抗 |
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Cytokeratin 4 (KRT4)
Rabbit Monoclonal Antibody |
| 別????名： |
KRT4 antibody, CK4 antibody, CYK4 antibody, FLJ31692 antibody, K4 antibody, Keratin, type II cytoskeletal 4 antibody, Type-II keratin Kb4 antibody |
| 貨號 |
品名 |
規格 |
包裝 |
單價 |
貨期 |
庫存 |
| 1227177688 |
Cytokeratin 4 (KRT4) |
|
100ul |
詢價 |
現貨 |
3天 |
| 提示信息：偏遠地區如新疆西藏寧夏甘肅等地可能無法運送液體，下單前請聯系客服。 |
| 性 狀： |
【反應特異性】Human
【克隆 ID】EP1599Y
【用途】WB , IHC , ICC , FC , IP
【抗原分子量】59kDa |
| 質量標準： |
【產品介紹】Keratins are a family of structurally
related proteins that form the intermediate
filament cytoskeleton in epithelial cells. White
sponge nevus (WSN) is a benign autosomal dominant
disorder which affects non-cornifying stratified
squamous epithelial. Keratins are expressed in pairs
by epithelial cells in a tissue and cell specific
manner. The major differentiation specific keratins of
the buccal mucosa, nasal, esophageal and
anogenital epithelia are CK-4 and CK-13. The
tissue distribution and nature of the lesions in
patients affected by WSN suggested that mutations in
CK-4 and/or CK-13 might be responsible for this
disorder (1). K4 and K13 form heterodimers in
normal epithelial cells. In humans, K4 is present in
all layers of the epidermis at 10 weeks and
gradually disappears, starting from the basal layers at
15 weeks and becoming totally absent at around 20
weeks. This period corresponds to the early fetal
period when melanoblasts derived from the neural
crest migrate through the dermis into the basal layer of
the epidermis (2).
Recommended Applications
WB, IHC, ICC, IP, FC
Applications and Recommended Dilution Factors WB: 1:500 - 1000
IHC: 1:100 - 250
ICC: 1:50 - 100
IP: 1:10 - 100
FC: 1:100 - 500
Species Reactivity * Human *Cross reactivity determined by western blot only. Products Data
A. Western blot analysis on A431 cell lysate
using anti-Cytokeratin 4 RabMAb (cat. # 1994-1). B. Immunohistochemical staining of
paraffin-embedded cervical carcinoma using
anti-Cytokeratin 4 RabMAb (cat. #1994-1). Specificity A synthetic peptide corresponding to residues on
the C-terminus of human Cytokeratin 4 was used as
an immunogen. |
| 貯 存： |
Storage Condition and Buffer Store at -20 °C. Buffer: 50 mM Tris-Glycine (pH 7.4),
0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and
0.05% BSA. Stable for 12 months from date of receipt. |
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