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| 生化科研試劑 >> 抗體產品 >> 一抗 |
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Ezrin Rabbit Antibody
Rabbit Monoclonal IgG |
| 別????名： |
p81, Cytovillin, Villin-2 |
| 貨號 |
品名 |
規格 |
包裝 |
單價 |
貨期 |
庫存 |
| 1227177772 |
Ezrin Rabbit Antibody |
|
100ul |
詢價 |
現貨 |
3天 |
| 提示信息：偏遠地區如新疆西藏寧夏甘肅等地可能無法運送液體，下單前請聯系客服。 |
| 性 狀： |
【反應特異性】Human , Mouse , Rat
【克隆 ID】EP924Y
【用途】WB , ICC , FC
【抗原分子量】81 kDa |
| 質量標準： |
【產品介紹】Erzin, a member of the Ezrin, Radixin,
Moesin (ERM) family, is a linker protein located
between cell surface recept o r s, adhesion molecules,
a n d actin cytoskeleton (1-2). Ezrin activity is
regulated by intramolecular interactions between
N- a n d C-terminal ERM association domains (3).
Erzin tyrosine phosph o r ylation can also be induced
by EGF, PDGF a n d HGF stimulation. Erzin interacts
with PI3-K protein kinase A a n d Rho (4). In response
to epidermal growth fact o r (EGF) the microvillar
c o r e protein ezrin is phosph o r ylated transiently to
a high level on tyrosine residues in human
epidermoid carcinoma A431 cells. Tyr145, lies in
the N-terminal region of homology that is common to the
b a n d 4.1-talin-ezrin protein family. This
tyrosine residue a n d its vicinal amino acids are
conserved throughout the family members, including
radixin, moesin, a n d the two phosphotyrosine
phosphatases, PTP H1 a n d PTP MEG, but not in b a n d 4.1
o r talin (5).
WB: 1:1000 - 5000
ICC: 1:100 – 250
Flow Cytometry: 1:20
A. Western blot analysis on (A) 293, (B) A431
a n d (C) SH-SY5Y cell lysate using anti-Ezrin RabMAb
(cat. # 2255-1), dilution 1:10,000.
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